Eur Rev Med Pharmacol Sci 2017; 21 (22): 5290-5296

DOI: 10.26355/eurrev_201711_13854

Ethical and medico-legal remarks on uterus transplantation: may it solve uterine factor infertility?

S. Zaami, E. Marinelli, N.M. di Luca, G. Montanari Vergallo

Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Rome, Italy. enrico.marinelli@uniroma1.it


Uterus transplantation was firstly tested with animal trials sixty-five years ago. Despite several successful attempts in human subjects, the different procedures still lay at the experimental stage, in need of further studies and investigations before they can be considered as standard clinical practices. Uterus transplant cannot be regarded as a life-saving procedure, but rather a method to restore woman ability to procreate, when lost, thus improving her quality of life. Uterus transplant is a complex surgical procedure and presents significant health threats. Medical staff should therefore always obtain informed consent from patients, emphasizing such risks. Before that, women undergoing uterine transplants should be thoroughly informed about the hazards inherent to the procedure and especially about the dangers of immunosuppressant drugs, administered after the surgery which may injure the fetus, eventually formed in the restored organ and even lead to its death, thus nullifying the purpose of the transplant itself. Therefore, the risk-benefit ratio of uterus transplantation needs to be carefully assessed and described.

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To cite this article

S. Zaami, E. Marinelli, N.M. di Luca, G. Montanari Vergallo
Ethical and medico-legal remarks on uterus transplantation: may it solve uterine factor infertility?

Eur Rev Med Pharmacol Sci
Year: 2017
Vol. 21 - N. 22
Pages: 5290-5296
DOI: 10.26355/eurrev_201711_13854