OBJECTIVE: We aimed to investigate the heart rate variability in children with myocarditis presenting with ventricular arrhythmias.
PATIENTS AND METHODS: The study compared the characteristics of heart rate variability (HRV) among 67 children with viral myocarditis (VMC), presenting with (n=35) and without (n=32) ventricular arrhythmias and a control group of 30 healthy children.
RESULTS: Compared with the control group, the HRV time-domain indicators of children with VMC were significantly lower (p<0.05); also, the indicators of children with ventricular arrhythmias were significantly lower than those of children without ventricular arrhythmias (p<0.05). Equally, during both the lucid and sleep periods, the time-domain indicators of HRV were significantly lower in patients with VMC and arrhythmias than in either the control group (p<0.05) or the group with VMC but no ventricular arrhythmias (p<0.05).
CONCLUSIONS: We conclude that the HRV of children with VMC probably decreased because of impaired vagal nerve function, with ventricular arrhythmias developing only when the decrease was most significant. Thus, HRV can be a useful predictive indicator for ventricular arrhythmias in children with VMC.Free PDF Download
To cite this article
N. Ling, C.-L. Li, Z.-Z. Wang, H.-N. Zhang, H. Xu, X.-J. An
Heart rate variability in children with myocarditis presenting with ventricular arrhythmias
Eur Rev Med Pharmacol Sci
Vol. 22 - N. 4