OBJECTIVE: The purpose of this study was to investigate the effect of the heparanase inhibitor OGT2115 on the tumorigenic properties of KB oral cancer cells. MATERIALS AND METHODS: We treated KB cells with different concentrations of OGT2115. Then proliferation, invasion, and migration were detected using different assays. Cell cycle was explored using flow cytometry. RESULTS: … Continue reading Mechanisms of OGT2115 inhibition of invasion and migration in KB oral cancer cells