MiR-101 affects proliferation and apoptosis of cervical cancer cells by inhibition of JAK2

OBJECTIVE: JAK2 expression and dysfunction play a role in tumor pathogenesis. Bioinformatics analysis revealed a targeted binding site between miR-101 and the 3’-UTR of JAK2 mRNA. This study investigated the role of miR-101 in regulating JAK2 expression and affecting the proliferation and apoptosis of cervical cancer cells. PATIENTS AND METHODS: The tumor tissues and adjacent … Continue reading MiR-101 affects proliferation and apoptosis of cervical cancer cells by inhibition of JAK2