MiR-1266 suppresses the growth and metastasis of prostate cancer via targeting PRMT5

OBJECTIVE: To elucidate the correlation between microRNA-1266 (miR-1266) and prostate cancer (PCa) progression, and to investigate the possible underlying mechanism. PATIENTS AND METHODS: The expression level of miR-1266 and protein arginine methyltransferase 5 (PRMT5) in PCa tissues and cell lines was first detected by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR). After up-regulating or down-regulating miR-1266 … Continue reading MiR-1266 suppresses the growth and metastasis of prostate cancer via targeting PRMT5