Effect of exosome-carried miR-30a on myocardial apoptosis in myocardial ischemia-reperfusion injury rats through regulating autophagy

OBJECTIVE: To explore the effect of exosome-carried micro-ribonucleic acid-30a (miR-30a) on myocardial apoptosis in rats with myocardial ischemia-reperfusion injury (MIRI) and its possible regulatory mechanism. MATERIALS AND METHODS: The MIRI rat model was established via ligation of the left anterior descending coronary artery. A total of 30 Sprague-Dawley (SD) rats were randomly divided into Sham … Continue reading Effect of exosome-carried miR-30a on myocardial apoptosis in myocardial ischemia-reperfusion injury rats through regulating autophagy