OBJECTIVE: The aim of this study was to investigate the effect of atorvastatin on pulmonary arterial hypertension (PAH) in rats and to observe its specific regulatory mechanism through the phosphatidylinositol 3-hydroxy kinase/protein kinase B (PI3K/AKT) signaling pathway. MATERIALS AND METHODS: The model of PAH was successfully established in rats via hypoxia feeding. All rats were … Continue reading Effect of atorvastatin on pulmonary arterial hypertension in rats through PI3K/AKT signaling pathway