OBJECTIVE: Recovery of blood flow after ischemic cardiomyopathy can lead to aggravation of myocardial injury. This is very detrimental to the patient’s prognosis. The purpose of this study was to investigate the effects and mechanisms of microRNA-140-5p (miR-140-5p) on myocardial ischemia-reperfusion injury (IRI). MATERIALS AND METHODS: We made the myocardial IRI model in rats and … Continue reading MiR-140-5p targets BCL2L1 to promote cardiomyocyte apoptosis