Eur Rev Med Pharmacol Sci 2018; 22 (4): 1161-1167

DOI: 10.26355/eurrev_201802_14405

Medical use of cannabis: Italian and European legislation

S. Zaami, A. Di Luca, N. M. Di Luca, G. Montanari Vergallo

Department of Anatomical, Histological, Forensic and Orthopedic Sciences, Sapienza University of Rome, Rome, Italy. l.montanarivergallo@libero.it


This review illustrates some brief considerations of the medical use of cannabis recently issued in Italy. History and uses of cannabis throughout centuries and different countries are illustrated together with a description of botany and active phytocannabinoids. Then, medical use of cannabis anti-pain treatment for patients resistant to conventional therapies is described in case of chronic neuropathic pain, spasticity, for anticinetosic and antiemetic effect in nausea and vomiting caused by chemotherapy, for appetite stimulating effect in cachexia, anorexia, loss of appetite in cancer patients or patients with AIDS and in anorexia nervosa, hypotensive effect in glaucoma resistant to conventional therapies and for reduction of involuntary body and facial movements in Gilles de la Tourette syndrome. Italian most recent legislation on medical cannabis is detailed with some law proposals, also showing the inconsistent legislation within European Union. Some final considerations of future studies are also reported.

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To cite this article

S. Zaami, A. Di Luca, N. M. Di Luca, G. Montanari Vergallo
Medical use of cannabis: Italian and European legislation

Eur Rev Med Pharmacol Sci
Year: 2018
Vol. 22 - N. 4
Pages: 1161-1167
DOI: 10.26355/eurrev_201802_14405