OBJECTIVES: Aim of this work is to show the effectiveness of a protocol involving the use of platelet-rich plasma (PRP) as a grafting material in bone regeneration before dental implant rehabilitation.
MATERIALS AND METHODS: 127 patients, requiring maxillary sinus lift, were enrolled in a follow-up study plan, which established clinical and radiological examinations on the day after surgery and six months later. PRP, in combination with autogenous bone, anorganic bone material and organic bone substitutes, was used before implant-prosthetic rehabilitation.
RESULTS AND CONCLUSIONS: After implant placement, 63 patients, previously treated with PRP, reached a statistically significant improvement in implant-prosthetic rehabilitation, established by primary stability and radiographic integration criteria, in comparison with the other 64 patients receiving implant-prosthetic rehabilitation without PRP treatment.
Corresponding Author: Raffaele Cagiano, MD; e-mail: r.cagiano@farmacol.uniba.it
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F. Inchingolo 1,3, M. Tatullo 3,4,5, M. Marrelli 3,5, A.M. Inchingolo 6, A.D. Inchingolo 7, G. Dipalma 3, P. Flace 4, F. Girolamo 4, A. Tarullo 2, L. Laino 8, R. Sabatini 2, A. Abbinante 2, R. Cagiano 2
Regenerative surgery performed with Platelet-Rich Plasma used in sinus lift elevation before dental implant surgery: an useful aid in healing and regeneration of bone tissue
Eur Rev Med Pharmacol Sci
Year: 2012
Vol. 16 - N. 9
Pages: 1222-1226