OBJECTIVE: Septic arthritis and osteomyelitis are rare in children, but they are difficult to treat and are associated with a high rate of sequelae. This paper addresses the main clinical issues related to septic arthritis and osteomyelitis by means of a systematic review of systematic reviews.
MATERIALS AND METHODS: The major electronic databases were searched for systematic reviews/meta-analyses septic arthritis and osteomyelitis. The papers that fulfilled the inclusion/exclusion criteria were selected.
RESULTS: There were four systematic reviews on septic arthritis and four on osteomyelitis. Independent assessment of their methodological quality by two reviewers using AMSTAR 2 indicated that its criteria were not consistently followed.
CONCLUSIONS: Collectively, these works provide strong evidence regarding a large number of issues including classification, epidemiology and risk factors, causative organisms, clinical presentation, laboratory markers, imaging, diagnostic needle aspiration, antibiotic therapy, surgical therapy, and prognosis. A clinical summary based on the best evidence is supplied.Free PDF Download
To cite this article
A. Gigante, V. Coppa, M. Marinelli, N. Giampaolini, D. Falcioni, N. Specchia
Acute osteomyelitis and septic arthritis in children: a systematic review of systematic reviews
Eur Rev Med Pharmacol Sci
Vol. 23 - N. 2 Suppl