Eur Rev Med Pharmacol Sci 2019; 23 (13): 5531-5534

DOI: 10.26355/eurrev_201907_18285

The use of dermal regeneration template (Pelnac®) in a complex upper limb trauma: the first Italian case report

N. Scuderi, P. Fioramonti, B. Fanelli, P. Fino, C. Spalvieri

Department of Plastic and Reconstructive Surgery, University of Rome, Sapienza, Rome, Italy. pasquale.fino@gmail.com


Dermal regeneration template (DRT) has been well widely implicated in the reconstruction of full-thickness injury. We present our experience and our clinical application of Pelnac® to achieve wound closure with complex acute, upper limb, full-thickness defect post-trauma. A 22-year-old boy presented a soft tissues loss of the back of the hand and forearm with tendon’s involvement and exposure. The wound was treated with Pelnac®; the silicone layer was removed at postoperative day 30 and dermal regeneration template was reapplied at the level of the residual tendon exposure; a split-thickness skin graft (0.2 to 0.3 mm) was inserted. Clinically, the reconstructed areas demonstrated good granulation tissue at 14 days with a good take of the skin graft. There were no major acute graft loss, rejection or associated infections cells through downregulating TLR4 expression.

Free PDF Download

To cite this article

N. Scuderi, P. Fioramonti, B. Fanelli, P. Fino, C. Spalvieri
The use of dermal regeneration template (Pelnac®) in a complex upper limb trauma: the first Italian case report

Eur Rev Med Pharmacol Sci
Year: 2019
Vol. 23 - N. 13
Pages: 5531-5534
DOI: 10.26355/eurrev_201907_18285