Eur Rev Med Pharmacol Sci 2020; 24 (1): 345-351

DOI: 10.26355/eurrev_202001_19932

Relationship of asthma control test scores with pulmonary function tests, quality of life and adiposity in asthmatic children

S.S. Habib, M. Alsuhaim, A. Alzahrani, A. Alsaud, K. Alzahrani, S. Aldawsari, K. Alhendas, M. Al Saadi, S. Bashir

Department of Physiology, College of Medicine and King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia. shahidhabib44@hotmail.com


OBJECTIVE: This study aimed at assessing asthma control test (ACT score), quality of life (QOL), and pulmonary functions in asthmatic children, and to see the correlations between ACT score, QOL, and pulmonary functions.

PATIENTS AND METHODS: This cross-sectional study was conducted at the departments of pediatrics and physiology, College of Medicine, King Saud University Medical City (KSUMC), Riyadh, Saudi Arabia. A total of 109 (53 asthmatics and 56 controls) children (aged 6 to 13 years) of both genders were studied. All subjects underwent clinical evaluation, 36-Item Short Form Survey (SF-36) for QOL, Spirometry, and cognitive assessment through mini mental state examination (MMSE).

RESULTS: QOL showed significantly lower scores in asthmatic compared to non-asthmatic children. The higher social functioning [SF] (p=0.0012) and less role limitation due to physical health [RLPH] (non-asthmatic patients had had higher physical functioning [PF] (p=0.0001), less energy/fatigue [EF] (p=0.0008=0.0068). On the opposite side, no significant difference was found regarding role limitations due to emotional problems [RLEP] (p=0.0644) and Emotional well-being [EW] (p=0.0758) between the two groups. A significant positive correlation was seen between QOL items and ACT score in PF (r=.535, p<0.01), less RLPH (r=.593, p<0.01), less FE (r=.379, p<0.01), higher EW (r=.310, p<0.05), and higher SF (r=.495, p<0.01). No significant correlation was found between body mass index (BMI) and lung functions in children with asthma. Interestingly, a positive correlation was found in asthmatic children between BMI and MMSE scores (r=.298, p=0.030).

CONCLUSIONS: Our study concluded that QOL in asthmatic patients was significantly lower than healthy subjects in terms of patient’s physical functioning and social life. However, the emotional aspects of QOL were not significantly affected in asthmatic children.

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S.S. Habib, M. Alsuhaim, A. Alzahrani, A. Alsaud, K. Alzahrani, S. Aldawsari, K. Alhendas, M. Al Saadi, S. Bashir
Relationship of asthma control test scores with pulmonary function tests, quality of life and adiposity in asthmatic children

Eur Rev Med Pharmacol Sci
Year: 2020
Vol. 24 - N. 1
Pages: 345-351
DOI: 10.26355/eurrev_202001_19932