Eur Rev Med Pharmacol Sci 2020; 24 (8): 4554-4557

DOI: 10.26355/eurrev_202004_21040

Could host cell receptor alteration prevent SARS-CoV-2 viral entry? – Hype or hope

M. Paulpandi, K. Kavithaa, A. Asaikkutty, V. Balachandar, N. Ayyadurai, N. Arul

Disease Proteomics Laboratory, Department of Zoology, School of Life Sciences, Bharathiar University, Coimbatore, TN, India. curlyproteomics@gmail.com


Cell-surface receptors are the inviters of many potent pathogens that can adjust to any kind of circumstance for their existence. Many of these organisms are highly resistant to the currently existing drugs and mutate to new strains with high levels of pathogenesis, posing life-threatening consequences. Owing to such concerns, antiviral strategies are being assessed based on host cell receptor targeting. Many natural compounds with a tendency to strip off the cell surface receptors are under evaluation. Compounds that are non-toxic, patient friendly, and yield a quick output are essential for the current scenario. Drugs targeting the cell surface receptors should, therefore, be developed and standardized for the effective management of SARS-CoV-2 viral infection.

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To cite this article

M. Paulpandi, K. Kavithaa, A. Asaikkutty, V. Balachandar, N. Ayyadurai, N. Arul
Could host cell receptor alteration prevent SARS-CoV-2 viral entry? – Hype or hope

Eur Rev Med Pharmacol Sci
Year: 2020
Vol. 24 - N. 8
Pages: 4554-4557
DOI: 10.26355/eurrev_202004_21040