Eur Rev Med Pharmacol Sci 2020; 24 (17): 9196-9201

DOI: 10.26355/eurrev_202009_22871

Pathogenic analysis of suspected COVID-19 patients in a SARS-CoV-2 non-epidemic area of China

Y.-H. Ji, T. Qi, Y. Ding, Q. Ruan, Y.-P. Ma

Virology Laboratory, Shengjing Hospital of China Medical University, Liaoning, China. mayp@sj-hospital.org


OBJECTIVE: The aim of this study is to find the distributions of pathogens in 164 suspected COVID-19 patients from the outpatient clinic of Shenjing Hospital of China Medical University from 24th January, 2020, to 29th February of 2020.

PATIENTS AND METHODS: 164 COVID-19 suspected patients were from the Shengjing Hospital of China Medical University. Oropharyngeal swab specimens were acquired by respiratory doctors under standardized conditions. Specific nucleic acids of SARS-CoV-2, influenza A and B, respiratory syncytial virus A and B, adenovirus, parainfluenza virus, along with pneumonic mycoplasma were detected by real-time fluorescence PCR. Symptomatic, epidemiologic, laboratory and radiological data of the patients were obtained from the electronic medical record system of our hospital.

RESULTS: Among the 164 patients, 3 were positive for SARS-CoV-2, 15 were positive for other respiratory viruses and 16 were positive for pneumonic mycoplasma. Of the positive patients above, 1 patient was co-infected with SARS-CoV-2 and adenovirus, and 1 was co-infected with influenza B and pneumonic mycoplasma. The 3 SARS-CoV-2 infected patients were clinically diagnosed as COVID-19 because they meet the diagnostic criteria listed in “Chinese Clinical Guidance for COVID-19 Pneumonia diagnosis and treatment”, including epidemic history, symptom and pathogenic detection, as well as abnormalities of the laboratory and radiological data. However, the clinical characteristics of COVID-19 patients were non-specific compared to those of the patients infected with other respiratory viruses.

CONCLUSIONS: The endemic common respiratory pathogens are more prevalent than SARS-CoV-2 in the SARS-CoV-2 non-epidemic areas of this research. Detection of the pathogen is the unique means for definite COVID-19 diagnosis.

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To cite this article

Y.-H. Ji, T. Qi, Y. Ding, Q. Ruan, Y.-P. Ma
Pathogenic analysis of suspected COVID-19 patients in a SARS-CoV-2 non-epidemic area of China

Eur Rev Med Pharmacol Sci
Year: 2020
Vol. 24 - N. 17
Pages: 9196-9201
DOI: 10.26355/eurrev_202009_22871