Eur Rev Med Pharmacol Sci 2021; 25 (4): 2050-2055

DOI: 10.26355/eurrev_202102_25109

Relapsing polychondritis associated with heart block

J.F. de Carvalho, L.C. Behrmann Martins, A.F. Cardoso, Y. Shoenfeld

Institute for Health Sciences from Federal University of Bahia, Salvador, Bahia, Brazil. jotafc@gmail.com


OBJECTIVE: The present article aims at describing a rare case of an RP patient who evolved with heart block and was successfully treated with corticoid pulse therapy, without the need for pacemaker insertion.

PATIENTS AND METHODS: A systematic research on relapsing polychondritis (RP) and heart block (HB) published in PubMed/MEDLINE, Web of Sciences, LILACS, and Scielo from 1966 to August 2020 was performed.

RESULTS: It was found 10 studies on RP associated with HB, and we added a case. Most were male (7/10) with ages 30 to 66 years old. RP disease duration was 1 week-6 years. In most cases (7/10), the RP was active when the HB occurred. A complete HB was observed in 4/7, followed by type II degree block in 3/7, and one patient had a sinus node dysfunction. Most patients received glucocorticoids. A pacemaker was inserted in 4/9 cases. Good outcome was observed in 3/9 patients and mortality in 2/10.

CONCLUSIONS: We report the first case of an RP patient who had a heart block and was successfully treated with methylprednisolone pulse therapy. The authors suggest that in these RP cases, an attempt with a glucocorticoid pulse therapy may be offered to treat the heart block and prevent the insertion of a pacemaker.

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To cite this article

J.F. de Carvalho, L.C. Behrmann Martins, A.F. Cardoso, Y. Shoenfeld
Relapsing polychondritis associated with heart block

Eur Rev Med Pharmacol Sci
Year: 2021
Vol. 25 - N. 4
Pages: 2050-2055
DOI: 10.26355/eurrev_202102_25109