Multimodal therapy for hepatocellular carcinoma: the role of surgery

L. Mocan

“Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania, lucian.mocan@umfcluj.ro

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• Oncology

OBJECTIVE: Liver cancer is one of the widest spread malignancies in the world and its incidence is still on the rise. The surgical resection of liver cancer has become a widely performed procedure with considerably improved outcomes, low mortality rate, transfusions, and post-op bed stay.

MATERIALS AND METHODS: Our goal with this paper was to conduct a narrative review of the literature in regard to the surgical treatment of hepatocellular carcinoma (HCC).

RESULTS: There are various modalities of treatment for the HCC, e.g., hepatic resection, LT, or radiofrequency ablation (RFA) – the selection of a specific treatment regimen plays a decisive role in the survival rate of the patient and this, in turn, is guided by factors like size and distribution of lesion and the stage of malignancy. A more efficient patient selection for each treatment increases the survival rate of the patients in each subgroup.

CONCLUSIONS: Surgical procedures play a crucial role in treatment of hepatocellular carcinoma as part of a multimodal therapy.

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