Eur Rev Med Pharmacol Sci 2021; 25 (19): 5922-5927

DOI: 10.26355/eurrev_202110_26868

A case of chronic systemic capillary leak syndrome (SCLS) exacerbated during SARS-CoV2 infection

A. Concistrè, F. Alessandri, E. Rosato, F. Pugliese, M. Muscaritoli, C. Letizia

Department of Translational and Precision Medicine, University “Sapienza”, Rome, Italy. claudio.letizia@uniroma1.it


Systemic capillary leak syndrome (SCLS) is a very rare and lethal disease characterized by hemoconcentration and hypoalbuminemia caused by reversible plasma extravasation. The underlying cause for SCLS remains largely unknown and acute treatment has remained mainly supportive. Prophylaxis with intravenous immunoglobulin (IVIG) has been shown to successfully prevent further episodes in affected patients. We reported a case of SCLS in a patient who presented to our hospital with COVID-19 and developed profound shock.

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To cite this article

A. Concistrè, F. Alessandri, E. Rosato, F. Pugliese, M. Muscaritoli, C. Letizia
A case of chronic systemic capillary leak syndrome (SCLS) exacerbated during SARS-CoV2 infection

Eur Rev Med Pharmacol Sci
Year: 2021
Vol. 25 - N. 19
Pages: 5922-5927
DOI: 10.26355/eurrev_202110_26868