Eur Rev Med Pharmacol Sci 2022; 26 (17): 6192-6198

DOI: 10.26355/eurrev_202209_29636

A single-center kidney transplantation experience in children with low weight: is low weight a contraindication?

E. Eren, M. Tokac, O. Ozkaya, O. Anil Savas, A. Sümer, A. Dinckan

Department of General Surgery, Department of Pediatric Nephrology, Istinye University, Istanbul, Turkey. prfdrazizsumer@gmail.com


OBJECTIVE: Kidney transplantation (KT) might be difficult for underweight kids (under 15 kg). Our goal was to convey information on KT in underweight children.

PATIENTS AND METHODS: The study’s target population consisted of children (age 18) weighing 15 kg or fewer who received KT at our facility between January 2018 and June 2021. A retrospective analysis was performed on demographic and clinical data, including age, gender, primary disease, pretransplant dialysis status, recipient weight, recipient body mass index (BMI), surgical approach type (intraperitoneal/extraperitoneal), complications, graft status (functioning/failed), patient survival, and immunological data.

RESULTS: There were 94 pediatric KTs completed. Thirty-three patients were included when the selection criteria were applied. The mean recipient weight was 11.45 [6.7-15] kg, and the average patient age was 3.36 [1-7]. Three (9.9%) patients had kidney transplants from dead adult donors, whereas thirty (90.1%) patients underwent live donor kidney transplantation (LDKT). While the intraperitoneal (IPA) technique was used in 19 cases, the extraperitoneal (KT) strategy was used on 14 patients (EPA). The donor BMI was 28.24 [19.6-42] kg/m2, and the mean donor weight was 78.13 [55-109] kg. Bridectomy was necessary because five individuals experienced ileus. IPA was performed in each of these patients during LDKT. Following IPA, a 2-year-old patient with a BMI of 16 kg/m2 had renal allograft compartment syndrome and required graft nephrectomy.

CONCLUSIONS: Pediatric patients weighing 15 kg or fewer can get kidney transplants successfully. Gastrointestinal problems are relatively uncommon with EPA, even though there is no agreement on the best surgical strategy.

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To cite this article

E. Eren, M. Tokac, O. Ozkaya, O. Anil Savas, A. Sümer, A. Dinckan
A single-center kidney transplantation experience in children with low weight: is low weight a contraindication?

Eur Rev Med Pharmacol Sci
Year: 2022
Vol. 26 - N. 17
Pages: 6192-6198
DOI: 10.26355/eurrev_202209_29636