The effect of standard, ketogenic, and Western-type diets applied to rats in pressure wound therapy

S. Çetinkaya Özdemir, H. Sert, H. Çakiroğlu, Ö. Budak

Department of Internal Medicine Nursing, Faculty of Health Science, Sakarya University, Sakarya, Turkey. serapc@sakarya.edu.tr

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• Nutrition

OBJECTIVE: This study aimed at investigating the effect of ketogenic and Western diets on pressure wounds.

MATERIALS AND METHODS: This randomized controlled study used 33 male Sprague-Dawley rats. They were randomly divided into the control, ketogenic, and Western diet groups. Pressure wounds were created on the rats’ backs.

RESULTS: Wound healing of the Western diet group on day 42 was better than the ketogenic and standard groups. In the microscopic examinations, wound closure, damaged muscle tissue repair, angiogenesis, vascularization, granulation, and collagenization in the Western diet group were faster than in the ketogenic and standard groups.

CONCLUSIONS: The Western diet was potentially effective for pressure wound healing. Future research should be conducted to clarify how this affects the wound-healing process.

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