Wettability of mg-ha/Chitosan-based membrane surfaces: blood vs. autologous platelet liquid (APL)

F. Lorusso, C. Mortellaro, A. Greco Lucchina, G. Falisi, C. Bugea, A. Tampieri, M.S. Di Carmine, A. Scarano

Department of Innovative Technologies in Medicine and Dentistry, University of Chieti-Pescara, Chieti-Pescara, Italy. ascarano@unich.it

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• Regenerative Medicine

OBJECTIVE: The physical and physical chemistry is able to influence the interaction of the scaffolds and bone substitutes with the body fluid and blood. The aim of the present investigation was to evaluate the wettability properties of an Mg-HA Chitosan-based Gel with blood vs. autologous platelet gel.

MATERIALS AND METHODS: A total of 6 study groups were evaluated according to the Mg-HA Chitosan-based Gel thickness (1, 2 and 3 mm) and the fluids (blood vs. autologous platelet gel). The biomaterial wettability was conducted through the sessile drop technique.

RESULTS: The study findings showed a significant difference in contact angle between the APL and blood groups (p<0.05). The MG-Ha Chitosan-based membrane thicknesses seem to produce no significant effects on contact angles measurement for all groups (p>0.05).

CONCLUSIONS: In the present investigation, a similar MG/Ha gel membranes wettability was reported between APL and blood groups. In addition, a high hydrophilicity of MG/Ha gel membranes was reported with a potential advantage in terms of a more effective osteogenic capability in the clinical practice.

Published on: 2023/04/27

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