The value of microbiology rapid on-site evaluation of sepsis caused by pulmonary infection

P. Yan, Q.-X. Hao, L.-C. Song, X.-L. Wang, F. Wang, Q.-Y. Yang, K.-F. Wang, Y. Tao, L.-X. Xie, G.-X. Mo

China Aerospace Science & Industry Corporation 731 Hospital, Beijing, China. 13661005996@139.com

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• Infectious Diseases

OBJECTIVE: This study aims to evaluate the value of microbial rapid on-site evaluation (M-ROSE) of sepsis, and septic shock caused by pulmonary infection.

PATIENTS AND METHODS: Thirty-six patients with sepsis and septic shock due to hospital-acquired pneumonia were analyzed. Accuracy and time were compared with M-ROSE, traditional culture, and next-generation sequencing (NGS).

RESULTS: A total of 48 strains of bacteria and 8 strains of fungi were detected by bronchoscopy in 36 patients. The accuracy rate of bacteria and fungi was 95.8% and 100%, respectively. M-ROSE took an average of 0.34±0.01 hours, much faster than NGS (22h±0.01 h, p<0.0001) and traditional culture time (67.50±0.91 h, p<0.0001).

CONCLUSIONS: M-ROSE may quickly identify common bacteria and fungi, so it may be a useful method for the etiological diagnosis of sepsis and septic shock caused by pulmonary infection.

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