Bibliometric analysis of intestinal microbiota in diabetic nephropathy

L.-W. Gao, X.-Y. Yang, Y.-F. Yu, S. Yin, K.-K. Tong, G. Hu, W.-X. Jian, Z. Tian

College of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China. 86385568@qq.com

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• Diabetes

OBJECTIVE: The purpose of this study is to use bibliometrics to explore the research overview and research hotspots.

MATERIALS AND METHODS: The relevant literature on intestinal flora and diabetic nephropathy in the Web of Science Core Collection was sorted out, and VOSviewer, CiteSpace, Scimago Graphica and other software were used to conduct data visualization analysis on the number of publications, countries, institutions, journals, authors, keywords and citations.

RESULTS: A total of 124 relevant literatures were included. From 2015 to 2022, the number of published papers increased every year. The countries, institutions and journals that published the most articles in this field are China, Isfahan University Medical Science and Frontiers in Pharmacology. Liu Bicheng and Mirlohi Maryam are the authors with the most published articles in this field. The main keywords of research in this field are obesity, inflammation, oxidative stress, indoxyl sulfate, short-chain fatty acids (SCFAs) and Chinese herbal medicine.

CONCLUSIONS: This is the first bibliometric analysis of diabetic nephropathy and gut microbiota, reporting hot spots and emerging trends. Obesity, inflammation, oxidative stress, indoxyl sulfate, SCFAs and Chinese herbal medicine are the main keywords of current research, and SCFAs and Chinese herbal medicine may be the hotspots of future research.

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