Eur Rev Med Pharmacol Sci 2024; 28 (2): 577-583
DOI: 10.26355/eurrev_202401_35055

Impact of adenomyosis on pregnancy outcomes: a retrospective consecutive cohort study

L.-S. Chen, X. Chen, J.-R. Song, Y.-L. Zhuang, X. Xie, S.-H. Liu, X.-Q. Zheng, H. Yi, Y.-L. Zhang

Department of Obstetrics and Gynecology, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China. edisen90@163.com


OBJECTIVE: This retrospective study explored the potential connection between adenomyosis and pregnancy outcomes.

PATIENTS AND METHODS: A study included data from a total of 1,208 pregnancies. The adenomyosis group included 334 pregnant women with adenomyosis, and women in the control group (n=874) had uncomplicated pregnancies. Data on pregnancy complications and maternal and neonatal outcomes were compared.

RESULTS: The incidence of gestational hypertension, gestational diabetes, and placenta previa was higher in the adenomyosis group compared to the control group (p<0.05). Adenomyosis was linked to a higher risk of postpartum hemorrhage (1,000-1,500 ml) but a lower risk of premature rupture of membranes (PROM) (p<0.05). Diagnosis of adenomyosis correlated with increased incidence of low fetal weight (20.3% vs. 21.3%, p<0.05) and a low APGAR score at 1 min (p<0.05).

CONCLUSIONS: Adenomyosis correlated with a higher incidence of gestational hypertension, placenta previa, and gestational diabetes. At the same time, adenomyosis correlated with a significantly lower incidence of PROM compared to uncomplicated pregnancy. There was a significant increase in the incidence of postpartum hemorrhage and a higher risk of low fetal weight and lower APGAR score at 1 min in pregnancies with adenomyosis.

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To cite this article

L.-S. Chen, X. Chen, J.-R. Song, Y.-L. Zhuang, X. Xie, S.-H. Liu, X.-Q. Zheng, H. Yi, Y.-L. Zhang
Impact of adenomyosis on pregnancy outcomes: a retrospective consecutive cohort study

Eur Rev Med Pharmacol Sci
Year: 2024
Vol. 28 - N. 2
Pages: 577-583
DOI: 10.26355/eurrev_202401_35055