Acute fatty liver with pancreatitis in pregnancy after in vitro fertilization – literature review and case report

C.C. Vaduva, S. Saceanu, D. Cartu, M.B. Novac, M.V. Boldeanu, A.M. Goganau, L. Dira, L. Boldeanu

Department of Obstetrics and Gynecology, University of Medicine and Pharmacy, Craiova, Romania. mihail.boldeanu@umfcv.ro

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• Obstetrics
• Reproductive Medicine

BACKGROUND: Acute fatty liver disease in pregnancy (AFLP) is a low-incidence condition that usually affects women in the third trimester of pregnancy or the early postpartum period. This article reviews recent advances in the diagnosis and treatment of AFLP with pancreatitis in pregnancy induced by in vitro fertilization (IVF).
CASE REPORT: A rare case of AFLP and pancreatitis occurred in a pregnant woman with an IVF-induced twin pregnancy delivered by cesarean section. Diagnosis of this condition is difficult, and delay in accurate diagnosis and timely and appropriate treatment can lead to serious complications such as acute pancreatitis or extensive damage to multiple organs and systems, which can have significant consequences. The main therapeutic approach was the rapid administration of drugs accompanied by therapeutic measures to support liver function and pancreatic complications.
CONCLUSIONS: We would like to reemphasize the importance of multidisciplinary management and rapid intervention in AFLP with acute pancreatitis after IVF.

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