Eur Rev Med Pharmacol Sci 2024; 28 (14): 4029-4037
DOI: 10.26355/eurrev_202407_36578

A nomogram for predicting low cardiac output syndrome in older patients undergoing acute type A aortic dissection surgery

J.-B. Wu, L. Chen, X. Yang, Y. Liu, K.-Y. Chen, L.-W. Chen

Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, People’s Republic of China. chenkeyuan@fjmu.edu.cn


OBJECTIVE: Low cardiac output syndrome (LCOS) is a dangerous postoperative complication in patients with acute type A aortic dissection (ATAAD). This study aims to develop and evaluate a nomogram model that can reliably identify risk variables for postoperative LCOS in elderly patients suffering from ATAAD.

PATIENTS AND METHODS: In this retrospective study, a total of 310 elderly patients with ATAAD admitted to Fujian Medical University Union Hospital were included and categorized into the LCOS and non-LCOS groups. Stepwise logistic regression was used to analyze independent predictors of LCOS, and a nomogram was constructed. The best clinical decision points were found using decision analysis and a clinical impact curve.

RESULTS: Postoperative LCOS occurred in 22 (7.1%) of elderly patients with ATAAD. Independent risk factors for postoperative LCOS were age, smoking history, aortic cross-clamp (ACC), coronary heart disease (CHD), and preoperative shock. The nomogram constructed based on the identified risk factors showed good performance.

CONCLUSIONS: Our results suggest that preventive treatment can be administered when needed when the risk of LCOS in older patients with ATAAD after surgery is >60%. This study contributes to developing a methodology that may improve therapeutic decision-making in older patients and provides insights for assessing the risk of LCOS.

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To cite this article

J.-B. Wu, L. Chen, X. Yang, Y. Liu, K.-Y. Chen, L.-W. Chen
A nomogram for predicting low cardiac output syndrome in older patients undergoing acute type A aortic dissection surgery

Eur Rev Med Pharmacol Sci
Year: 2024
Vol. 28 - N. 14
Pages: 4029-4037
DOI: 10.26355/eurrev_202407_36578