Abstract. – Lampito mauritii, an earthworm widely used in Siddha as well as Ayurveda, has been reported to have anti-inflammatory, anti-ulceral and anti-oxidative properties. The present investigation shows its hepatoprotective role. Whole tissue extract of Lampito mauritii protect the paracetamol (2 g/kg body weight. p.o.) induced liver damage rat as a dose dependent manner (100, 200 and 300 mg/kg body weight p.o.) by significantly (P < 0.05) decreasing the hepatic marker enzymes – aspartate transaminase, alanine transaminase and alkaline phosphatase similar to silymarin (150 mg/kg b.w. p.o.). Histopathological observations of liver tissues corroborated these findings.
Corresponding Author: M. Balamurugan, MD; e-mail: firstname.lastname@example.orgFree PDF Download
To cite this article
Restoration of histoarchitecture in the paracetamol-induced liver damaged rat by earthworm extract, Lampito mauritii (Kinberg)
Eur Rev Med Pharmacol Sci
Vol. 11 - N. 6