Eur Rev Med Pharmacol Sci 2008; 12 (4): 275-280

A suitable test for identifying high risk adult patients of moderate-severe obstructive sleep apnea syndrome

M. Casale, V. Rinaldi, F. Bressi#, V. Di Peco, P. Baptista°, B. Sadun*, E. Urrestarazu**, M. Trivelli, F. Salvinelli

Department of Otolaryngology, Campus Bio-Medico University, Rome (Italy) #Department of Neurology, Campus Bio-Medico University, Rome (Italy) *Department of Statistics, Campus Bio-Medico University, Rome (Italy) °Department of Otolaryngology, Clinica Universitaria de Navarra, Pamplona (Spain) **Clinical Neurophysiology Section, Department of Neurology, Clinica Universitaria de Navarra, Pamplona (Spain)


The aim of this study was the evaluation of the usefulness of a 7-items questionnaire, Rome Questionnaire (RQ), in identifying adult patients at risk of obstructive sleep apnoea syndrome (OSAS).
136 adults (76 M, 60 F) with snoring were enrolled. Each patient underwent to an overnight polysomnography (PSG) study and the patient’s bed partner answered the “RQ”. RQ survey items mainly addressed the presence and frequency of snoring behaviour, breathing pauses, sore throat, oral breathing and wake time sleepiness.
Of the 136 initial patients, 111 (63 M, 48 F; mean age 54.6 ± 10.84) with a complete PSG examination were included in the study. They were divided according to apnea-hypopnea index (AHI) into two groups: group A with a primary snoring or mild OSAS (AHI ≤ 15) and group B with moderate-severe OSAS (AHI > 15). The RQ final score was 25.27 ± 16.1 for group A and 42.29 ± 15.2 for group B, with a statistically significant (p < 0.0001) difference. Analyzing the RQ score of group B (moderate-severe OSAS) we surprisingly noticed that most of patients (66%) showed an high RQ score (> 40). No patients with moderate-severe OSAS showed a RQ score < 20 and for every point scored in the questionnaire there is an extra 1.07 (0.7%) risk of belonging to group B.
Group B showed a mean body mass index (BMI) of 31.53 (± 4.95), significantly (p < 0.001) higher than BMI of group A (26,86 ± 3.28) and BMI results a good predictive factor (p = 0.013) of mild-severe OSAS.
In conclusion, the “RQ”, together with BMI, seems to be an useful tool to make a selection of the patients at higher risk of moderate-severe OSAS, who need a prompt PSG evaluation. Our findings will require further validation in larger sample of subjects.

Corresponding Author: Manuele Casale, MD; e-mail: m.casale@unicampus.it

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M. Casale, V. Rinaldi, F. Bressi#, V. Di Peco, P. Baptista°, B. Sadun*, E. Urrestarazu**, M. Trivelli, F. Salvinelli
A suitable test for identifying high risk adult patients of moderate-severe obstructive sleep apnea syndrome

Eur Rev Med Pharmacol Sci
Year: 2008
Vol. 12 - N. 4
Pages: 275-280