Antibacterial activity of Acalypha indica L.

M. Govindarajan1, A. Jebanesan1, D. Reetha2, R. Amsath3, T. Pushpanathan1, K. Samidurai4

1Division of Vector Biology, Department of Zoology, Annamalai University, Tamilnadu (India)
2Department of Microbiology, Faculty of Agriculture, Annamalai University, Tamilnadu (India)
3Khadir Mohideen College, Tamilnadu (India)
4CAS in Marine Biology, Annamalai University, Tamilnadu (India)

---

• Pharmacology

Abstract. – Hexane, chloroform, ethyl acetate and methanol extracts from the leaves of Acalypha indica were tested against Gram-positive (Staphylococcus aureus, Staphylococcus epidermidis, Bacillus cereus, Streptococcus faecalis) and Gram-negative (Klebsiella pneumoniae, Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa) bacteria. All the extracts exhibited antibacterial activity against Gram-positive organisms with minimum inhibitory concentrations (MIC) between 0.156 to 2.5 mg/ml. Among the Gram-negative bacteria, only the Pseudomonas aeruginosa was susceptible to the extracts.

Corresponding Author: M. Govindarajan, MD; e-mail: drgovind1979@rediffmail.com

Free PDF Download