BACKGROUND AND OBJECTIVES: Epidemiological and interventional studies suggest that a high dietary intake of n-3 polyunsaturated fatty acids may confer a protective effect against atherosclerotic disease and reduce serum triglycerides levels. The aim of our study was to investigate the effectivity on triglyceride levels and inflammatory markers of a concentrated of n-3 fatty acids in patients with type 2 diabetes mellitus and hypertriglyceridaemia.
SUBJECTS: A total of 30 patients (16 males and 14 females) with diabetes mellitus type 2 and hypertriglyceridemia (>200 mg/dl) were included in the study. Patients received two capsules of eicosapentaenoic 465 mg and docosahexanoic 375 mg daily for 12 weeks.
RESULTS: Triglycerides levels and non HDL-cholesterol decreased (326±113.5 vs. 216.4±57 mg/dl; p In conclusion, an n-3 polyunsaturated intervention improved lipid profile and inflammatory markers in patients with diabetes mellitus type 2 and hypertriglyceridaemia.
Corresponding Author: Daniel A. de Luis, MD; e-mail: firstname.lastname@example.orgFree PDF Download
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To cite this article
D.A. de Luis, R. Conde, R. Aller, O. Izaola, M. González Sagrado, J.L. Perez Castrillón, A. Dueñas, E. Romero
Effect of omega-3 fatty acids on cardiovascular risk factors in patients with type 2 diabetes mellitus and hypertriglyceridemia: an open study
Eur Rev Med Pharmacol Sci
Vol. 13 - N. 1