Protein-loosing enteropathy in sclerosing mesenteritis

A. Rispo, M. Sica, L. Bucci, D. Musto, L. Camera, G. Ciancia, G. Luglio, N. Caporaso

Gastroenterology, Colorectal Surgery, Radiology, Pathology; Department of Clinical Medicine and Surgery, University “Federico II” of Naples, Italy. antoniorispo@email.it

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• Gastroenterology

Sclerosing mesenteritis (SM) is a rare, idiopathic disorder of unknown aetiology that involves the adipose tissue of the mesentery, being characterized by chronic and non-specific fibrous inflammation. Patients usually present with non-specific clinical manifestations, such as abdominal pain and diarrhoea. The diagnosis of SM is difficult and it can be definitely established only by means of surgical or imaging-guided biopsy. Different therapeutic strategies have been used in case series with different rate of success. The disease is generally self-limiting, and the long-term prognosis is good, even if some cases of severe SM are reported in literature. Here, we report a fatal case of sclerosing mesenteritis associated to protein-losing enteropathy.

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