Eur Rev Med Pharmacol Sci 2015; 19 (12): 2301-2302

Mucosal lichenoid drug reaction associated with glimepiride: a case report

S. Hammami, K. Ksouda, H. Affes, Z. Sahnoun, K. Zeghal

Department of Pharmacology, Faculty of Medicine of Sfax, Sfax, Tunisia. hammamj_serria@yahoo.fr

We report the case of a 52-year-old man with type 2 diabetes, who developed severe mucosal erosions of the tongue, glans penis and perianal area, induced by glimepiride. A tissue biopsy was performed and revealed the characteristics of lichen planus (LP). The improvement of the patient’s condition after withdrawal of glimepiride added to recurrence of the lesions when medication was reintroduced confirmed that the second generation anti-diabetic was the causative agent. To the best of our knowledge, this has not been reported previously.

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To cite this article

S. Hammami, K. Ksouda, H. Affes, Z. Sahnoun, K. Zeghal
Mucosal lichenoid drug reaction associated with glimepiride: a case report

Eur Rev Med Pharmacol Sci
Year: 2015
Vol. 19 - N. 12
Pages: 2301-2302

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