Novel information on the genetic factors involved in the development of diseases

S.M. Kotelevets, Z.M. Galeeva, Z.B. Karakotova, S.A. Chekh

Department of Therapy, Medical Institute, North Caucasus State Academy of Humanities and Technology, Cherkessk, Russian Federation. smkotelevets@mail.ru

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• Genetics

Nowadays full-genome sequencing allows achieving revolutionary progress in the modern medicine. As the result of a huge work on the study of the human genome and based on the results obtained, one can conclude that the single nucleotide polymorphisms are the reasons of the vast majority of non-communicable diseases as well as the diseases other than injuries and poisoning, i.e. the diseases where the cause is not obvious. To clarify the role of single nucleotide polymorphism in the occurrence of atrophic gastritis, it is required to perform full-genome sequencing and human genome scanning with a simultaneous mass serological screening of atrophic gastritis. As a result, it will be possible to establish which single nucleotide polymorphism is responsible for mild, moderate, and severe mucosal atrophy in the antrum and the body of the stomach. Serological screening of mild, moderate, and severe mucosal atrophy in the antrum and the body of the stomach can be made using GastroPanel.

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