Systemic effects of the pesticide mancozeb – A literature review

J.C. Dall’Agnol, M. Ferri Pezzini, N. Suarez Uribe, D. Joveleviths

Occupation Health, Federal University of Rio Grande do Sul State – UFRGS, Porto Alegre, Brazil. juulianacristina@hotmail.com

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• Pharmacology

OBJECTIVE: The purpose of this literature review is to document what has already been scientifically published about the pesticide Mancozeb and its potential systemic complications.

MATERIALS AND METHODS: Data were collected during the months of July, August and September 2020, from the Medline and PubMed databases, in the Portuguese, English and Spanish, covering articles written in the last 20 years. Twenty-one studies were selected for analysis.

RESULTS: The results found in this review study, indicate that Mancozeb is potentially damaging to health, appearing as an increase in ethylethiourea (ETU) dosages in most studies.

CONCLUSIONS: About the widespread use of Mancozeb, the studies found show that this fungicide is a potential cause of several health problems, mainly hepatic, renal and genotoxic, demonstrating with an increase in ETU dosages, as well as liver enzymes in most studies, corroborating the idea that the deliberate use of the product can induce potential systemic complications, and is a public health problem.

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