Can Type 1 diabetes progression be halted? Possible role of high dose vitamin D and omega 3 fatty acids

F. Cadario, S. Savastio, A.M. Rizzo, D. Carrera, G. Bona and C. Ricordi

Division of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy. francesco.cadario@gmail.com Diabetes Research Institute and Cell Transplant Program, University of Miami Miller School of Medicine, Miami, FL, USA. CRicordi@med.miami.edu

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• Metabolism

In Type 1 Diabetes (T1D) in children, close to the onset the requirements of insulin are often reduced. This represents a transient recovery of endogenous insulin secretion named “honeymoon” because transient and followed by a progressive decline in C-peptide secretion. This case report describes the effect of administration of high dose vitamin D and Ω-3 fatty acids on T1D progression in a 8-year-old child. At today after one year and a half from the onset of T1D, the subject shows a near-normal blood glucose with the administration of 1.5-2 UI of insulin once a day. Thus this report may be of assistance to design additional studies to determine and validate the effect of administration of vitamin D and Ω-3 fatty acids on the progression of T1D.

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